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They included 12 SGLT2i trials with 73,238 participants, of whom 3,065 were on a GLP-1 RA: they found that the benefits of SGLT2i on MACE were consistent regardless of background GLP-1 RA use (HR = 0.81 in patients receiving GLP-1 RA vs HR = 0.90 in those not receiving GLP-1RA) with no significant heterogeneity (p = 0.31)

400 Calderoni, I

Patients with recurrent vulvovaginal candidiasis (four or more episodes annually) require more intensive treatment: an induction phase with fluconazole 150 mg every 72 hours for 2-3 doses or 10-14 days of topical therapy, followed by maintenance therapy with fluconazole 100-200 mg weekly for 6 months

Emerging applications of nanomedicine in dermatology

The lot number and expiration date should be clearly printed and match across the outer packaging, the vial, and any included documentation